SERUM ANTI- MULLERIAN HORMONE IS A BETTER PREDICTOR OF OVARIAN RESERVE AT THE EARLY FOLLICULAR PHASE.

Document Type : Original Article

Authors

1 Obstetrics & Gynecology Dpt, Faculty of Medicine, Alexandria University& Madina infertility private center

2 Obstetrics & Gynecology Dpt, Faculty of Medicine, Alexandria University.

Abstract

Objective : The study aim was to compare the relationship between serum anti-Mill lcrian hormone (AMH) levels and
other markers of ovarian reserve and to determine its predictive value.
Design: prospective randomized trial.
Setting : Alexandria University and IVF-ICSI Madina private center .
Patients : 60 infertile women under going IVF-ICSI programmes.
Main Outcome Measure (s): Comparison of early follicular ( day-3) scrum AMH levels among women with less than
five retrieved oocytes and five or more oocytes. Antral follicle count, mature oocyte count, age, basal
follicle-stimulating hormone (FSH), inhibin B, cstradiol (E0), serum E2 levels at day of hCG , and pregnancy success
were also compared .
Result (s): The mean serum AMH levels of patients with more than five retrieved oocytes were significantly higher
(0.67 ± 0.41 vs. 0.15 ± 0.11 pg/ml). Mature oocyte counts, antral follicle counts, and maximum E2 levels were found to
be statistically significantly different in the two groups despite the homogeneity of ages and levels of basal FSH and E2-
Conclusion(s): This suggests that AMH may reflect ovarian follicular status better than the usual hormone markers.

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