Objectives : To study the effect of addition of low dose of rccombinant follicle stimulating honiionc(r-FSH) in culture media on oocytc maturation, fertilization, cleavage and pregnancy rates in women with polycyslic ovaries, Material and Methods : In a randomized study of 100 women in an IVF program, 50 patients with 674 germinal vesicle (GV) oocytes were allocated to study the effect of low concentration dose of r-FSH (0.0 and O.075) supplemented in culture media on oocytes maturation, fertilization, cleavage, and pregnancy rate. Results : Oocytc maturation rate significantly (P<0.05) increased from 47% al 0.0 (control) to 81% at 0.075 IU/ml of r-FSH concentration, respectively. Fertilization, cleavage, and clinical pregnancy rates showed a similar trend and significantly increased from 45% to 83% and from 32% to 80% and from 0 to 17% at the two r-FSH concentrations, respectively. Conclusions : The results suggested that r-FSH supplementation in the culture media concentration of 0,075 IU was optimum in the present study and improved GV maturation, fertilization, cleavage and pregnancy rales.
Samy, I. (2008). Department of Obstetrics and Gynecology, King Abdulaziz University, Jeddah, Saudi Arabia. The Egyptian Journal of Fertility of Sterility, 12(1), 3-8. doi: 10.21608/egyfs.2008.4868
MLA
Ismail Samy. "Department of Obstetrics and Gynecology, King Abdulaziz University, Jeddah, Saudi Arabia". The Egyptian Journal of Fertility of Sterility, 12, 1, 2008, 3-8. doi: 10.21608/egyfs.2008.4868
HARVARD
Samy, I. (2008). 'Department of Obstetrics and Gynecology, King Abdulaziz University, Jeddah, Saudi Arabia', The Egyptian Journal of Fertility of Sterility, 12(1), pp. 3-8. doi: 10.21608/egyfs.2008.4868
VANCOUVER
Samy, I. Department of Obstetrics and Gynecology, King Abdulaziz University, Jeddah, Saudi Arabia. The Egyptian Journal of Fertility of Sterility, 2008; 12(1): 3-8. doi: 10.21608/egyfs.2008.4868
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