Effect of Prophylactic Negative Pressure Wound Therapy versus Standard Wound Dressing on Surgical-Site Infection Cesarean section in Obese Women: a randomized controlled trial

Abdelraouf, Abdelraouf Abdelnasser; Gouda, Hossam; Hassan, Moustafa; Taman, Mohamed

doi:10.21608/egyfs.2025.457883

Effect of Prophylactic Negative Pressure Wound Therapy versus Standard Wound Dressing on Surgical-Site Infection Cesarean section in Obese Women: a randomized controlled trial

Document Type : Original Article

Authors

Department of Obstetrics and Gynecology, Faculty of Medicine, Mansoura University, Egypt

10.21608/egyfs.2025.457883

Abstract

Background: Obesity is described as excessive fat accu-mulation presenting a risk to health. Caesarean delivery (CD) is the surgical approach by which a baby is deliv-ered through an abdominal incision in the mother. Surgi-cal site infections (SSIs) are a signiﬁcant postoperative adverse event. Negative pressure wound therapy (NPWT) is a modality frequently utilized to help major wounds close rapidly.
Aim: To assess the efﬁcacy of prophylactic NPWT, ini-tiated immediately after CD in lowering the risk of SSIs compared to traditional wound dressing in obese females on the occurrence of SSI.
Methods: This is a non-blinded Randomized Clinical Trial (RCT) conducted on 130 obese pregnant females underwent cesarean section randomly divided into two groups: Group A included 65 cases who had NPWT and Group B included 65 cases who had traditional wound dressing on SSI. The primary outcome was the SSI rate after two weeks of delivery.
Results: There was insigniﬁcant difference between group A and B regarding temperature, wound hotness, redness, painful sore, pus discharge and bad smell in week 1 (p>0.05), while there was a signiﬁcant difference was detected in week 2 between studied groups regarding temperature, hotness, redness, painful sores, bad smell and pus discharge. There was a statistically signiﬁcant decrease in painful sore and wound redness incidence for group A. There was difference between studied groups concerning SSI rate after 2 weeks with higher rate among group B compared to group A.
Conclusion: Our study concluded that the use of NPWT decreases the rate of SSI two weeks after delivery in obese women delivered by CS compared with traditional wound therapy.

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