Document Type : Original Article
Authors
1
Assistant professor Obstetrics and gynecology, Faculty of Medicine, Menoufia University, Menoufia, Egypt
2
Professor of Obstetrics and gynecology Department, Faculty of Medicine, Menoufia University, Menoufia, Egypt
3
Assistant lecture of Obstatric and Gynycology ,Faculty of Medicine, Menoufia University, Menoufia, Egypt
4
Assistant professor of Clinical Pathology, Faculty of medicine –Menoufia University
Abstract
Background:
Objectives: Assess the effects of intraovarian injection of autologous PRP on ovarian reserve measures and preg-nancy prognosis in women with a history of low ovarian reserve.
Patients & Methods: At the Faculty of Medicine, Ob-stetrics and Gynecology department, the outcomes of 28 infertile patients with poor ovarian reserve was injected with autologous platelet-rich plasma (PRP) into her ova-ry, a procedure typically reserved for POR women., Ten days following the onset of menstruation, the patient un-derwent a PRP. The study Started from from May 2021 to August 2023. the study protocol was registerated by the faculty of medicine ethical scientific committee. (Ethical clearance letter number 218G/2017).
Results: No substantial relation was noticed among preg-nancy outcome with infertility duration (P=0.792), pre-AFC (P=0.457) and post AFC (p=0.483). There was no significant relation between pre and post (FSH, LH, AMH) (P>0.05). While, pre and post estradiol were significantly decreased among women with positive pregnancy out-come (34.93±0.12, 36.67±0.58) than women with neg-ative pregnancy outcome (48.60±20.13, 49.92±19.74), (P=0.003). There was no significant relation between pre and post ovarian volume, ovarian doppler (PSV1) and (PSV2), (P>0.05).
Conclusion: There was no substantial increase in the pregnancy rates, embryo formation, oocyte, antral folli-cle count, and Anti-Mullerian Hormone associated with intraovarian PRP injection.
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