Role of Hyaluronic Acid Intrauterine Injection in Asherman’s Syndrome in Women Undergoing Hysteroscopy

Document Type : Original Article

Authors

1 Professor of Obstetrics and Gynecology, Faculty of Medicine, Ain Shams University

2 Master degree, Resident of Obstetrics and Gynecology, Faculty of Medicine, Ain Shams University

3 Assistant Professor of Obstetrics and Gynecology, Faculty of Medicine, Ain Shams University

Abstract

Background: Asherman’s syndrome an acquired disorder resulting from pregnancy, childbirth, infection, uterine in-tervention or repair of abnormalities in the uterus (e.g., intrauterine septum, bicornuate uterus or myomectomy).    
Aim of the Work: Investigating the efficacy of injecting Hyaluronic acid intrauterine in Asherman’s patients using hyster oscopic adhesiolysis.   
Patients and Methods: This randomized clinical trial was conducted at Early Cancer Detection & Endoscopy Unit maternity hospital Ain Shams University from Janu-ary 2023 till March 2024. 
Results: The Cases Group showed an increase from 8.3% before treatment to 41.7% after treatment, while the Con-trol Group remained relatively stable at 33.3% both be-fore and after treatment. Similarly, the proportion of par-ticipants experiencing mild symptoms in the Cases Group increased from 33.3% before treatment to 50.0% after treatment, whereas the Control Group remained consis-tent at 33.3%. However, the reduction in amenorrhea in the case group compared to the control group, but an in-significant difference between the two groups.
Conclusion: Intrauterine adhesions can result from surgi-cal or hysteroscopic intervention, it can be corrected ef-fectively and safely with the use of hysteroscop to restore menstural pattern and fertility. 

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