A Cohort Study to Evaluate Correlation of Pre-Operative CA-125 and Intra-Operative Stage of Endometriosis

Document Type : Original Article

Authors

1 Lecturer of Obstetrics and Gynecology, Faculty of Medicine, Ain Shams University

2 Professor of Obstetrics and Gynecology, Faculty of Medicine, Ain Shams University

3 Master degree, Resident of Obstetrics and Gynecology Faculty of Medicine, Ain Shams University

Abstract

Background: Endometriosis is an estrogen-dependent gynecologic illness that affects many women's ability to conceive, their physical well-being, and their general quality of life.   
Objectives: To ascertain if the stage of endometriosis af-ter surgery and preoperative CA125 were correlated.    
Methods: Our study was conducted at Obstetrics and Gy-naecology Department, Ain Shams university hospitals and conducted on 60 patients with pelvic pain, endome-triotic cysts, known endometriosis.  
Results: The study involved patients aged 30.58 ± 6.19 years with a mean preoperative CA125 of 57.74 ± 127.09, with 93.3% ovarian, 1.7% ovarian, uterosacral ligament, 1.7% tubal, and 1.7% tubal & Douglas P. Adhesion types included no adhesion, filmy, dense, superficial, deep, and bowel wall infiltration. Stages were 25.0% stage 1, 8.3% stage II, 56.7% stage III, and 10.0% stage IV. Median pre-operative CA125 was 22 in stage 1 and 48.5 in stage 4.
Conclusion: The study found that ovarian lesions were the most common site of lesion in 93.3% of patients, with Stage III being the most common stage in 56.7%. The mean preoperative CA125 was 57.74±127.09, and no significant difference was found between endometriosis stages. 

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