Helicobacter Pylori Infection in Pregnant Women with Hyperemesis Gravidarum & Its Effect on Pregnancy Outcome.

Abdelaziz, Mohamed; El-Nahas, Khaled Mohamed; Ahmed, Abeer Bahaa; Mohammed, Tamer Yehia

doi:10.21608/egyfs.2024.349376

Helicobacter Pylori Infection in Pregnant Women with Hyperemesis Gravidarum & Its Effect on Pregnancy Outcome.

Document Type : Original Article

Authors

¹ M.B.B. Ch 2013, Resident in Obstetrics and Gynecology Department

² Ismailia General Hospital, (2017)

³ Professor of Obstetrics and Gynecology, Faculty of Medicine, Suez Canal University.

⁴ Professor of Obstetrics and Gynecology, Faculty of Medicine, Suez Canal University

⁵ Assistant Professor in Obstetrics and Gynecology Department, Faculty of Medicine, Suez Canal University

10.21608/egyfs.2024.349376

Abstract

Background: Numerous studies established a signiﬁcant positive correlation between HG and the presence of H. pylori.
Aim: This study aimed to assess the effects of helicobacter pylori infection among pregnant women with hyperemesis gravidarum on pregnancy outcome.
Patients and Methods: This cross-sectional study was conducted on 180 pregnant females with hyperemesis gravidarum. Women were assigned to one of two groups: Group A: pregnant women with hyperemesis gravidarum, who were tested positive for the presence of H. pylori infection and group B: pregnant women with hyperemesis gravidarum, who were tested negative for the presence of H. pylori infection.
Results: Group A had signiﬁcantly higher percentage of abortion, past history of HG and family history of HG than group B with statistically signiﬁcant differences as p<0.05. Group A had signiﬁcantly lower mean of hemoglobin than group B with statistically signiﬁcant differences as p<0.001. While group A had higher mean of random blood sugar than group B with statistically signiﬁcant differences as p=0.014. Women in group B showed signiﬁcantly higher resolution of HG than group A (p<0.001). Women in group B showed signiﬁcantly higher resolution of HG and weight gain than group A (p<0.001). Group A had higher incidence of preterm labor and neonates with low birth weight than group B with statistically signiﬁcant differences.
Conclusion: Although a link between H. pylori and HG has previously been established, this paper makes an important contribution to the literature by conﬁrming this relationship among Egyptian women.

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