Evaluation of serum progesterone on the day of human chorionic gonadotropin administration as a predictor of pregnancy rate in ICSI

Document Type : Original Article

Authors

1 Lecturer of obestatics and gynecology faculty of medicine ,Ain Shams University Consultant obestatics and gynecology Pulse care medical center ,Hafr El Batin ,KSA

2 2) Department of obstetrics & gynecology- Al-Azhar University, Cairo, Egypt

3 3) Department of obstetrics & gynecology- Al-Galaa Teaching hospital, Cairo, Egypt

4 1) Department of obstetrics & gynecology- Ain-Shams University, Cairo, Egypt

Abstract

Introduction: Increase in serum P4 levels alongside high estradiol (E2) levels may lead to endometrial gland  stroma asynchrony, which can lead consequently to implantation failure. Aim: Is to investigate the role of serum progesterone level on the day of  hCG administration as a predictor of pregnancy  in ICSI.  
Methods: a prospective observational clinical study included fifty infertile women undergoing ICSI. The main outcome of the study was to evaluate the role of serum progesterone on the day of hCG administration as a predictor of pregnancy rate in ICSI.    
Results: serum progesterone level at the day of hCG administration is not a useful predictor of pregnancy in cases undergoing ICSI. Conclusion: Serum progesterone at the day of hCG is not a useful predictor of pregnancy outcome. Further studies with larger numbers are needed to confirm or refute this finding. 

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