Role of prophylactic antibiotics in preventing pelvic infection after surgical management of first-trimester miscarriage

Document Type : Original Article

Authors

1 Assistant Professor of Obstetrics and Gynecology, Department of Obstetrics and Gynecology, Faculty of Medicine-Cairo University, Cairo, Egypt.

2 Obstetrics and Gynecology resident, Bolak Eldakror hospital, Department of Obstetrics and Gynecology, Bolak Eldakror hospital, MOH, Cairo, Egypt.

3 Professor of Obstetrics and Gynecology, Department of Obstetrics and Gynecology, Faculty of Medicine-Cairo University, Cairo, Egypt.

4 Lecturer of Obstetrics and Gynecology, Department of Obstetrics and Gynecology, Faculty of Medicine-Cairo University, Cairo, Egypt.

Abstract

Background: Prophylactic antibiotics have been tradi- tionally used to prevent postoperative infection after sur- gical intervention for the first-trimester miscarriage. This work aims to study the role of prophylactic antibiotics in preventing pelvic infection after surgical management of first-trimester miscarriage.
Methods: This study was conducted on 138 women who underwent surgical management of first-trimester mis- carriage. They were equally divided into two groups; the women in the study group were given a single dose of oral doxycycline (200 mg) and metronidazole (500 mg) 2 hours before the surgical procedure. The other group was given a placebo. Both groups were followed up for assessment of postoperative infection within two weeks.  
Results: According to the original strict criteria, the preva- lence of pelvic infection was found in 8.7% in the antibiotic group (6 out of 69) and 13% in the placebo group (9 out of 69), P=0.412. On follow-up, there was no significant differ- ence between the studied groups concerning postoperative complications.     
Conclusion: Prophylactic antibiotics before the surgical in- tervention of first-trimester miscarriage resulted in an insig- nificant decrease in postoperative pelvic infection.

Keywords

Files

Share

How to cite

Statistics