Objective: Evaluate the impact of high number of retrieved oocytes on the outcome of ICSI cycles.
Material and methods: A retrospective study performed in Mansoura integrated fertil- ity center. We reviewed 1566 ICSI cycles and compared the patient, cycle features and cycle outcome of ICSI for high responders (> 15 retrieved oocytes corresponding to > 75th percentile) and normal responders (5- 15 oocytes between 25th and 75th percentile). Results: High responders were significantly younger and thinner than the normal respond- ers. The oocyte maturation was significantly lower in high responders. Fertilization rate, Implantation rate and the clinical pregnancy rate revealed significant differences being lower in high responders.
Conclusion: High oocyte yield is detrimental to ICSI outcome. It does not only affect the maturation of oocyte but also affects the fertilization, the implantation and the clinical pregnancy rate.
Wael Refaie, E. R. (2012). The influence of high responders on the outcome of intracytoplasmic sperm injection. The Egyptian Journal of Fertility and Sterility, 16(2), 29-32. doi: 10.21608/egyfs.2012.257781
MLA
Ehsan Refaie, Wael Refaie. "The influence of high responders on the outcome of intracytoplasmic sperm injection", The Egyptian Journal of Fertility and Sterility, 16, 2, 2012, 29-32. doi: 10.21608/egyfs.2012.257781
HARVARD
Wael Refaie, E. R. (2012). 'The influence of high responders on the outcome of intracytoplasmic sperm injection', The Egyptian Journal of Fertility and Sterility, 16(2), pp. 29-32. doi: 10.21608/egyfs.2012.257781
VANCOUVER
Wael Refaie, E. R. The influence of high responders on the outcome of intracytoplasmic sperm injection. The Egyptian Journal of Fertility and Sterility, 2012; 16(2): 29-32. doi: 10.21608/egyfs.2012.257781