Clinical outcome of day 5 and day 6 blastocyst vitrification

Document Type : Original Article

Author

Department of Obstetrics and Gynecology, Zagazig School of Medicine, Zagazig University, Egypt

Abstract

Objective:
to compare survival, clinical pregnancy and ongoing pregnancy rates of blastocysts
vitrified on day 5 and those which had one day delay and vitrified on day 6.
Materials & Methods:
The study included 210 vitrified warmed cycles, 135 patients underwent vitrifivation
at day 5 (group I) and 75 patients at day 6 (group II). Blastocyst survival and clinical pregnancy/embryo transfer were primary outcomes. Ongoing pregnancy/embryo
transfer was the secondary outcome.
Result(s)
blastocyst post-warming survival rates were comparable between both groups (92.9%
(263/283) of day 5 versus 94.9% (166/175) of day 6 blastocysts). There was no statistically significant difference between the 2 groups regarding the mean number
of transferred blastocysts. Clinical pregnancy rates were 40.6% (52/128) & 43.7%
(31/71) in women who undergone vitrification at day 5and day 6 respectively with no
significant differences. Similarly, ongoing pregnancy rate was comparable between
the 2 groups, 37.5% (48/128) versus 39.4% (28/71) in groups I & II.
Conclusion(s):
blastocysts vitrified on day 5 have the same survival, clinical and ongoing pregnancy
rates of blastocysts which had one day delay and vitrified on day 6.

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