Background: The Doppler examination of fetal and maternal blood vessels is one of the most important evaluation tools of the blood supply to the embryo specially when intrauterine growth restriction(IUGR) diagnosed during intrauterine life. We conducted an observational study to assess the role of Cerebro-Placental Doppler Ratio (CPR) in prediction of adverse perinatal outcome of IUGR. Methods: This prospective observational cohort study was conducted at Mansoura University Hospital-department of obstetrics and gynecology among 100 pregnant women diagnosed with IUGR. We performed two-dimensionalultrasound examination of fetus and placenta associated with Doppler waveform analysis of umbilical and middle cerebral arteries (UA & MCA). Estimation of CPR was performed by the following equation (MCA pulsatility index/ UA pulsatility index). Results: We divided our patients into two groups either with CRP <1 or with CRP ≥1.An emergencycesarean delivery (CD) was the dominant mode of delivery in 66.7% of cases with CPR<1, versus 35.4% in cases with CPR≥1. There was no statistically significant difference between both groups in the mean gestational age at delivery (35.38±1.53 & 36.15±1.77p=0.07) respectively. The mean neonatal weightswere (1497.6±227.2 gm& 1813.9±304.76 gm p < 0.001) in both groups respectively. All neonates with CPR<1were bornewith Apgar score< 7 at 5 minutes and were admitted to neonatal intensive care units (NICU). Only 62% of neonates were admitted to NICU when CPR was ≥1. Conclusion: Data from our study showed that the cutoff point for CPR is ≤1.1, and it has95.5% sensitivity in predicting adverse perinatal outcomes.
Mesbah, Y. (2021). Role of Cerebro-Placental Doppler Ratio in prediction of perinatal outcome in Intrauterine Growth Restriction. The Egyptian Journal of Fertility and Sterility, 25(3), 44-54. doi: 10.21608/egyfs.2021.195177
MLA
Yasser Mesbah. "Role of Cerebro-Placental Doppler Ratio in prediction of perinatal outcome in Intrauterine Growth Restriction", The Egyptian Journal of Fertility and Sterility, 25, 3, 2021, 44-54. doi: 10.21608/egyfs.2021.195177
HARVARD
Mesbah, Y. (2021). 'Role of Cerebro-Placental Doppler Ratio in prediction of perinatal outcome in Intrauterine Growth Restriction', The Egyptian Journal of Fertility and Sterility, 25(3), pp. 44-54. doi: 10.21608/egyfs.2021.195177
VANCOUVER
Mesbah, Y. Role of Cerebro-Placental Doppler Ratio in prediction of perinatal outcome in Intrauterine Growth Restriction. The Egyptian Journal of Fertility and Sterility, 2021; 25(3): 44-54. doi: 10.21608/egyfs.2021.195177