Intra-umbilical Oxytocin versus Methyl Ergometrine in the Third Stage of Labor: A Comparative Study from an Egyptian Tertiary Care Hospital

Document Type : Original Article

Author

Department of Obstetrics and Gynecology, Mansoura University Hospitals, Elgomhouria St., City 35111, Dakahlia, Egypt

Abstract

Abstract
Recently, the active management of the third stage of labor has
become a routine practice. In this study we compared two different ecobolics which were oxytocin and methyl ergometrine
through intra-umbilical route. The method: the trial divided the
included pregnant full term (>37 weeks) women in two groups
randomly; one for 0.2 mg methyl ergometrine and the second 10
units oxytocin. The outcomes were on the short term; estimated
blood loss (EBL), the need to add another ecobolic, vomiting,
blood pressure changes and the duration of the third stage, and
the long-term outcomes were hemoglobin levels and the need
for surgical or medical uterine evacuation. The results: the mean
blood loss was 155± 50.45ml and 167± 45.76 in the methyl ergometrine and the oxytocin groups respectively. Three cases in
the oxytocin group (3%) required additional methyl ergometrine
while in the ergometrine group only one case was given an additional oxytocin (1%). No vomiting was reported in both groups
and there were trivial changes in blood pressure. In the oxytocin group, the third stage duration was average 3.03± 1.02 min
in comparison to 2.98± 1.54min in the ergometrine group. Neither did those cases who were injected methyl ergometrine have
significant changes in the hemoglobin levels nor did they need
uterine evacuation. However, only one case in the oxytocin side
required blood transfusion due to uterine atony. Conclusion: intra-umbilical methyl ergometrine should be considered as an effective safe ecobolic in the third stage of labor.

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