Abstract Objectives: Interstitial ectopic pregnancy and pregnancy in a rudimentary horn of a unicornuate uterus are rare forms of ectopic pregnancy but carry a high risk for maternal morbidity and mortality. Their diagnosis is challenging and can be misdiagnosed with less dangerous conditions; namely: angular pregnancy or pregnancy in one side of septate or bicornuate uterus. This study aimed to differentiate between these four situations to allow early detection that will enhance the prognosis. Methods: This is a retrospective study, carried out on 26 patients referred to a private referral center for obstetric and gynecology sonography, in the period from November 2019 till November 2020. All cases were referred due to unusual eccenteric location of the gestational sac. In each case we assessed 3 variables using 2D -TVUS which were: relation to the endometrium , interstitial line sign and condition of the overlying myometrium. We assessed also 2 variables using 3D- TVUS which were: shape of the uterine cavity and the relation of the gestational sac to the uterotubal junction. Results: It was found that the gestational sac (GS) is within the endometrium in angular pregnancy and pregnancy in septate and bicornuate uterus while GS is outside the endometrial interface in interstitial ectopic pregnancy and pregnancy in rudimentary horn of unicornuate uterus. The interstitial line sign was +ve and the overlying myometrium was thin only in interstitial ectopic pregnancy. Cavity was normal in angular and interstitial ectopic pregnancy but it has a Mullerian fusion anomaly in cases of pregnancy in rudimentary horn of a unicornuate uterus and cases with pregnancy in one side of a septate or bicornuate uterus. GS was lateral to the uterotubal junction in interstitial ectopic pregnancy and pregnancy in rudimentary horn of unicornuate uterus but it was medial to it in the other 3 situations. Conclusion: Our study described a simple triaging model based on sonographic criteria for four pregnancy situations where the gestational sac appears eccenterically in the early 1st trimester. These four situations are namely; interstitial ectopic pregnancy, ectopic pregnancy in a rudimentary horn of a unicornuate uterus, angular pregnancy and pregnancy in one side of a septate or bicornuate uterus. This model will be helpful for early accurate diagnosis to avoid false positive diagnosis that may lead to unnecessary intervention and false negative diagnosis that may lead to maternal morbidity or mortality.
el-habashy, A. (2021). Triaging of eccentric gestational sac in early pregnancy using two dimensional and three dimensional transvaginal ultrasound. The Egyptian Journal of Fertility of Sterility, 25(2), 11-18. doi: 10.21608/egyfs.2021.169911
MLA
ahmed mahmoud el-habashy. "Triaging of eccentric gestational sac in early pregnancy using two dimensional and three dimensional transvaginal ultrasound". The Egyptian Journal of Fertility of Sterility, 25, 2, 2021, 11-18. doi: 10.21608/egyfs.2021.169911
HARVARD
el-habashy, A. (2021). 'Triaging of eccentric gestational sac in early pregnancy using two dimensional and three dimensional transvaginal ultrasound', The Egyptian Journal of Fertility of Sterility, 25(2), pp. 11-18. doi: 10.21608/egyfs.2021.169911
VANCOUVER
el-habashy, A. Triaging of eccentric gestational sac in early pregnancy using two dimensional and three dimensional transvaginal ultrasound. The Egyptian Journal of Fertility of Sterility, 2021; 25(2): 11-18. doi: 10.21608/egyfs.2021.169911